If I say that I have a genetic disease, my listener’s reflex is to think that the disease is “fixed”, “invariable”.
This was the view of early observers of genetic diseases.
Nowadays, it is clear that every disease “grows” on a terrain, a metabolism.

Since I began research on health disorders – 1979 – I suspected that many so called “genetic syndromes” have a fixed characteristic but also a great variability upon the environment – the terrain – of the syndrome.
This is confirmed in the case of the Ehlers-Danlos syndrome.
Mantle & coll write :
“(i) increasing scientific evidence that nutrition may be a major factor in the pathogenesis of many disorders once thought to result from defective genes alone
(ii) the recognition that many of the symptoms associated with Ehlers-Danlos syndrome are also characteristic of nutritional deficiencies
(iii) the synergistic action within the body of appropriate combinations of nutritional supplements in promoting normal tissue function. We therefore hypothesize that the symptoms associated with Ehlers-Danlos syndrome may be successfully alleviated using a specific (and potentially synergistic) combination of nutritional supplements, comprising calcium, carnitine, coenzyme Q(10), glucosamine, magnesium, methyl sulphonyl methane, pycnogenol, silica, vitamin C, and vitamin K.”

References

Mantle D, Wilkins RM, Preedy V. A novel therapeutic strategy for Ehlers-Danlos syndrome based on nutritional supplements. Med Hypotheses. 2005;64(2):279-83. doi: 10.1016/j.mehy.2004.07.023. PMID: 15607555.

Illustration : One of the possible characteristic is hyperlaxity.

Photo credit : WikiMedia